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Retinoids, differentiation, and disease.

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Published by Pitman, Distributed in North America by CIBA Pharmaceutical Co. in London, Newark, NJ, USA .
Written in English

Subjects:

  • Retinoids -- Physiological effect -- Congresses.,
  • Retinoids -- Therapeutic use -- Congresses.,
  • Cell differentiation -- Congresses.,
  • Cancer -- Chemotherapy -- Congresses.

Book details:

Edition Notes

SeriesCiba Foundation symposium ;, 113
ContributionsCiba Foundation., Symposium on Retinoids, Differentiation, and Disease (1984 : London, England)
Classifications
LC ClassificationsQP801.R47 R48 1985
The Physical Object
Paginationx, 286 p. :
Number of Pages286
ID Numbers
Open LibraryOL2637406M
ISBN 100272798134
LC Control Number85211988

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  Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant . This volume contains a comprehensive collection of methods for the isolation of platelet membranes, subcellular organelles, the cytoskeleton, and for the assay and purification of platelet receptors. Key Features* Platelets are cellular elements with the highest density of receptors per membrane surface area involved in binding of adhesive molecules, clotting, enzymes, and vasoactive amines.   Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and Author: Ayse Serap Karadag, Berna Aksoy, Lawrence Charles Parish. This symposium deals with the fundamental role of retinoids in the control of cell differentiation and cell proliferation, and the application of this know- ledge to the understanding and treatment of human disease. It is clear that research on retinoids has expanded far beyond its original domain of studies of nutrition and vision.

Book Description. This reference provides a comprehensive overview of recent developments in basic research that are relevant to the application of retinoids for cancer prevention and treatment.;Organized in a quick-referral format by specific disease site, this book: describes the effects of retinoids on squamous differentiation in normal, pre-malignant, and malignant epithelial tissues. Retinoic acid (RA) signaling pathways regulate essential biological functions, such as cell development, differentiation, proliferation, and apoptosis, and the expression of retinoid receptors is downregulated in several tumor types [4,10,14,15].RA signaling is crucial for mammalian post-implantation development and organogenesis, and vitamin A deficiency is associated with embryo and fetal. Title: Recent Advances in the Mechanisms of Action and Physiological Functions of the Retinoid-Related Orphan Receptors (RORs) VOLUME: 3 ISSUE: 4 Author(s):Anton M. Jetten Affiliation:Cell Biology Section, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC , USA. Abstract: Retinoids are a class of natural and synthetic vitamin A analogs structurally related to all-trans-retinoic acid (ATRA). Natural retinoids are involved in the physiology of vision and as morphogenic agents during embryonic development; they are also known to play a major role in regulating growth and differentiation of a wide variety of normal and malignant cell types, and, indeed.

ISBN: OCLC Number: Notes: "Symposium on Retinoids, Differentiation, and Disease, held at the Ciba Foundation, London, September "--Page v. Book: All Authors / Contributors: Ciba Foundation. ISBN: OCLC Number: Notes: "Symposium on Retinoids, Differentiation, and Disease, held at the Ciba Foundation, London, September "--Page v. Description: x, pages: illustrations ; 24 cm: Contents: What is a retinoid?   Retinoic acid, a vitamin A derivative that is used as a differentiation‐inducing agent in neuroblastoma treatment, is considered standard of care for children with high‐risk disease. 31 - 33 Nevertheless, it is not uniformly beneficial for all patients. Books Go Search EN Hello, Sign in Account & Lists Sign in Account & Lists Orders Try Prime Cart. Best Sellers Gift Ideas New Releases Whole Foods Today's Deals.